Hyperpolarized C MR Spectroscopic Imaging: Application to Brain Tumors
نویسندگان
چکیده
I. Park, P. E. Larson, S. Hu, R. Bok, T. Ozawa, J. Kurhanewicz, D. B. Vigneron, S. R. VandenBerg, C. D. James, and S. J. Nelson Bioengineering, University of California, San Francisco/Berkeley, San Francisco, CA, United States, Surbeck Laboratory of Advanced Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States
منابع مشابه
Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors.
In order to compare in vivo metabolism between malignant gliomas and normal brain, (13)C magnetic resonance (MR) spectroscopic imaging data were acquired from rats with human glioblastoma xenografts (U-251 MG and U-87 MG) and normal rats, following injection of hyperpolarized [1-(13)C]-pyruvate. The median signal-to-noise ratio (SNR) of lactate, pyruvate, and total observed carbon-13 resonances...
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